Actinic cheilitis is a precancerous lesion on the lip caused by chronic exposure to ultraviolet (UV) rays. It’s common in people who spend a great deal of time outdoors. For that reason, it’s sometimes called sailor’s lip or farmer’s lip.
You might mistake the symptoms, which include rough or swollen lips with whitish patches, for garden-variety chapped lips. But actinic cheilitis can progress to squamous cell carcinoma if left untreated. Squamous cell carcinoma can spread to the mouth and other parts of the body.
FAQs about Actinic Cheilitis
- They get more sun exposure because they protrude from the face. The lower lip typically protrudes further than the upper lip, so most actinic keratosis lesions form there.
- The skin of the lips is thinner than that of other parts of the body. It also has fewer sebaceous (oil) glands and less melanin, the pigment produced by skin to protect it from UV rays.
- Are over the age of 60
- Are male
- Have fair skin that burns or freckles easily
- Have worked outdoors for more than 25 years
- Have a history of nonmelanoma skin cancer
- Have a weakened immune system
- Scaly whitish patches on the lip
- Dryness or peeling that won’t heal
- A rough, sandpapery texture
- Blurring of the border between the lip and the adjacent skin
- Loss of color in the skin of the lip
- Swelling or redness of the lip
The most effective way to protect your lips from precancerous or cancerous lesions is to shield them from the sun whenever you’re outside, even on cloudy days and in the winter. Use a lip balm with SPF 30 or higher and apply it frequently. Wear a wide-brimmed hat that shades the front of your face, including your lips.
If you notice any changes to your lips that don’t resolve on their own, see a dermatologist promptly.
Actinic Cheilitis Treatment
Actinic cheilitis is treated with either an in-office surgery or topical medicine. The best treatment depends on the severity of the condition, how much area of the lip is involved and the location.
Surgical options include:
- Cryotherapy (freezing the lesion to remove it)
- Electrocautery (using an electric current to burn off the lesion), sometimes coupled with curettage to scrape it off
- CO2, pulsed dye or erbium laser treatment
- Vermilionectomy (surgery to cut out the lesion)
Topical treatments are typically used when the affected area is large. They include:
- Fluorouracil cream, also known as 5FU
- Imiquimod cream
- Ingenol mebutate gel
- Trichloroacetic acid, a type of chemical peel
- Diclofenac gel, a topical nonsteroidal anti-inflammatory drug



