Facebook Twitter Pinterest
Youtube Instagram Blog
Select Page

Pruritus: Treatment and Diagnosis

Who Gets Pruritus?
Diagnosis and Treatment of Pruritus

Pruritus is an itch or a sensation that makes a person want to scratch. Pruritus can cause discomfort and be frustrating. If it is severe, it can lead to sleeplessness, anxiety, and depression.

The exact cause of an itch is unknown. It is a complex process involving nerves that respond to certain chemicals like histamine that are released in the skin, and the processing of nerve signals in the brain.

Pruritus can be a part of skin diseases or internal disorders, or be due to faulty processing of the itch sensation within the nervous system.

Who Gets Pruritus?

There are many skin diseases like urticaria (hives), varicella (chicken pox), and eczema that may have itching associated with a rash. Some skin conditions only have symptoms of pruritus without having an obvious rash.

Dry skin can itch, especially in the winter, with no visual signs of a rash. Some parasitic infestations such as scabies and lice may be very itchy. Itchy, pigmented moles may be a sign of a malignant change.

Pruritus may be a manifestation of an internal condition. The most common example is kidney failure. Some types of liver disease like hepatitis, thyroid disease including both hyper (too much) and hypo (too little) thyroid hormone levels, some blood disorders such as lymphomas, iron deficiency anemia, polycythemia vera, multiple myeloma, and neurologic conditions such as pinched nerves and post-herpetic neuralgia can cause itching. Infectious diseases like HIV can cause severe itching.

Back to top

Diagnosis and Treatment of Pruritus

Often the Water’s Edge Dermatology practitioner will be able to diagnose these conditions with an examination; however, to determine a specific cause of the itch, a blood test, skin scraping, or biopsy may be needed to help make the diagnosis.

If the itch is due to a skin disease such as hives or eczema, treatment of the skin disease itself with prescription topical medications and/or oral antihistamines generally relieves the itch. If the itch is secondary to an internal disease, patients may require treatment of the disease, oral medication, or occasionally ultraviolet light therapy to relieve the itch.

Sometimes, the Water’s Edge Dermatology practitioner will prescribe a cooling topical lotion or cream and/or an oral medication to relieve the itch. Pruritus is often disrupting and difficult to control but usually responds well to treatment. While a specific identifying cause for the itch may not be found, an appropriate work-up to exclude internal disease should be completed.

Although there are many causes for pruritus, some basics apply to most treatments:

  • When bathing or showering, use tepid or lukewarm water.
  • Use mild cleansers with low pH.
  • Rinse soap film off completely, pat the skin lightly, and immediately apply a moisturizing lotion or cream after bathing.
  • Wear light, loose clothing.
  • A cool work or domestic environment can help reduce the severity of itching.
  • For itchy conditions where blistering or weeping of the skin is present, such as chicken pox or poison ivy, a cool oatmeal bath or topical drying agents such as calamine lotion can be helpful.

Back to top



No matter what time of day or night a skin problem or skincare need should appear, please use this form to request an appointment.

Request Now

Water's Edge Spotlight Read our Blog & Latest News

Keep up with the new WEderm Blog, a blend of insider info and latest news on medical & cosmetic dermatology, aesthetic skincare, plastic surgery, skin cancer diagnosis & treatment, vein health, and more.

Get the News

Water's Edge Dermatology Patient Education Library

From acne and alopecia to venous disease and vitiligo; get the definitions, explanations and facts you need about virtually any and all dermatologic conditions and skin diseases, in easy alphabetic order!

 Water's Edge Dermatology - Florida Dermatology - Dermatologist - Skin Diseases - Pediatric Dermatologist - Windermere Dermatology - types of warts - Venous Ulcers - Chronic Venous Insufficiency - Hives - Dermatologist in Sebastian, FL
Dermatologist in Sebastian, FL - Water's Edge Dermatology - Florida Dermatology - Dermatologist - Skin Diseases - Pediatric Dermatologist - Windermere Dermatology - Venous Ulcers - Chronic Venous Insufficiency - Hives - Sunscreens

WEderm Original Videos

Many of our dermatology providers are featured in the collection, and most leading skin disorders are covered. Learn more about prevention, diagnosis and treatment options for your condition, and hear what other patients have to say about us!

Translate »